PCNA Mouse Monoclonal Antibody [Clone ID: k1A3]

Specifications

Product Data
Clone Name	k1A3
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: 1/1,000~1/3,000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PCNA (1-261aa) purified from E. coli
Specificity	This antibody detects PCNA / Cyclin.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	proliferating cell nuclear antigen
Database Link	Entrez Gene 5111 Human UniProt ID P12004
Background	PCNA (Proliferating Cell Nuclear Antigen) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by UV irradiation, growth factors and eventually by neighboring tumors.
Synonyms	Cyclin
Reference Data

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