PD1 (PDCD1) (21-167) Mouse Monoclonal Antibody [Clone ID: 4F12]

Specifications

Product Data
Clone Name	4F12
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: 1/500 (starting dilution) - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PDCD1 (21-167aa) purified from E. coli
Specificity	This antibody detects PDCD1.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	programmed cell death 1
Database Link	Entrez Gene 5133 Human UniProt ID Q15116
Background	PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.
Synonyms	Protein PD-1, hPD-1, PDCD1
Reference Data

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