TAC1 Mouse Monoclonal Antibody [Clone ID: SP-DE4-21]

CAT#: AM02226PU-N

TAC1 mouse monoclonal antibody, clone SP-DE4-21, Purified



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CNY 4,851.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name SP-DE4-21
Applications ELISA, IF, IHC
Recommend Dilution ELISA: 1/10,000.
Immunohistochemistry on Vibratome Sections: 1/500-1/1,000.
Immunohistochemistry on Frozen Sections: 1/300 (Ref.2-4).
Specimen fixation not in Methanol.
Reactivity Guinea Pig, Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Synthetic Human Substance P.
Specificity The antibody reacts specifically with Substance P.
No cross reaction against related Tachykinins (Neurokinin A, Neurokinin B, and Kassinin).
Formulation PBS, pH 7.4
State: Purified
State: Lyophilized purified IgG fraction from Cell Culture Supernatant
Reconstitution Method Restore in aqua bidest to 1 mg/ml.
Concentration 1.0 mg/ml (after reconstitution)
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Prior to reconstitution store at 2-8°C.
Following reconstitution store undiluted at 2-8°C for one month 
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name tachykinin precursor 1
Background Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity.
Synonyms Substance-P
Note LocusID 6863 (tachykinin precursor contains: substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma).
Reference Data
Protein Families Druggable Genome, Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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