C1QA Mouse Monoclonal Antibody [Clone ID: 3R9/2]

CAT#: AM01324PU-N

C1QA mouse monoclonal antibody, clone 3R9/2, Purified



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CNY 7,502.00


货期*
4周

规格
    • 100 ul

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Specifications

Product Data
Clone Name 3R9/2
Applications ELISA, FC, IHC
Recommend Dilution ELISA.
Flow Cytometry.
Immunohistochemistry on Frozen Sections: It has been reported that this antibody works very well on acetone-fixed, frozen renal biopsies at a dilution of 1/500-1/600. Strong staining was observed in the glomeruli and in some cases the peritubular capillary (potentially clinically significant).
Recommended Positive Control: Kidney tissue from patients with streptococal glomerulonephritis.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Binds globular head domain of C1q, purified from human plasma.
Specificity This antibody recognises human complement component 1, q subcomponent (C1q), a 156kDa secreted protein.
Formulation Borate Buffered Saline, pH 8.4 containing 0.02% Sodium Azide as preservative.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Affinity Chromatography on Protein A.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name complement component 1, q subcomponent, A chain
Background C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
Synonyms Complement C1q, Complement 1q
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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