CLEC10A Rat Monoclonal Antibody [Clone ID: ER-MP23]

CAT#: AM01307PU-N

CLEC10A rat monoclonal antibody, clone ER-MP23, Purified



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CNY 7,538.00


货期*
4周

规格
    • 250 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name ER-MP23
Applications FC, IHC
Recommend Dilution Immunohistochemistry on Frozen Sections.
Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 10e6 cells in 100 µl.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Balb/c macrophage precursor cell hybrids.
Cells from immunised rats were fused with cells of the rat Y3-Ag1.2.3 myeloma cell line.
Specificity This antibody recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR).
Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name C-type lectin domain family 10 member A
Background In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.
Synonyms CLECSF13, CLECSF14, HML
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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