Ly86 Rat Monoclonal Antibody [Clone ID: MD113]

Specifications

Product Data
Clone Name	MD113
Applications	FC
Recommend Dilution	Flow cytometry: The typical starting working dilution is 1:50. Cannot be used for Western blot.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	The monoclonal antibody MD113 reacts with mouse MD-1. The antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.
Formulation	PBS Label: FITC State: Liquid 0.2 μm filtered Ig fraction Stabilizer: 1.0% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G
Conjugation	FITC
Storage Condition	Store at 2 - 8 °C.
Gene Name	lymphocyte antigen 86
Database Link	Entrez Gene 17084 Mouse UniProt ID O88188
Background	MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS.
Synonyms	Lymphocyte antigen 86, MD1
Reference Data

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