Cardiac Troponin T (TNNT2) Mouse Monoclonal Antibody [Clone ID: BGN/1288/44]

Specifications

Product Data
Clone Name	BGN/1288/44
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot (1/100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	HMW conjugate
Specificity	This antibody recognizes Troponin T Cardiac Isoform 1. Under reducing conditions, this antibody reacts with purified cardiac isoform in Western blotting and does not react with the skeletal isoform under the same conditions.
Formulation	PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	troponin T2, cardiac type
Database Link	Entrez Gene 7139 Human UniProt ID P45379
Background	Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.
Synonyms	cTnT, TnTc, TNNT2
Reference Data

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