KMP-11 Mouse Monoclonal Antibody [Clone ID: L157]

Specifications

Product Data
Clone Name	L157
Applications	ELISA, IF, WB
Recommend Dilution	ELISA: 1/2000. Immunoblotting: 1/1000-1/3000. Immunofluorescence: 1/500-1/1000.
Reactivity	Leishmania donovani
Host	Mouse
Clonality	Monoclonal
Immunogen	L. donovani lipophosphoglycan semi purified from epimastigotes.
Specificity	This antibody recognizes Kinetoplastid Membrane Protein 11 (KMP-11). Clone L-157 was originally derived against Leishmania donovani lipophosphoglycan, but found to recognise the tightly associated LPGAP. KMP-11 is found in a wide variety of Kinetoplastid parasites including African trypanosomes, Leishmania and Crithidia.
Formulation	State: Ascites State: Lyophilized Ascites Stabilizer: None Preservative: None
Reconstitution Method	Restore with 0.5 ml distilled sterile water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Database Link	UniProt ID Q36736
Background	Kinetoplastid Membrane Protein-11 (KMP-11), previously known as the lipophosphoglycan-associated protein (LPGAP), is an 11 kDa membrane protein. KMP11 may be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. It may be involved in parasite mobility and attachment to the surface of the host cell. It strongly stimulates T-cell proliferation and it is thought to play a role in the immunology of leishmaniasis.
Synonyms	KMP11, LPGAP
Reference Data

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