CD16 Mouse Monoclonal Antibody [Clone ID: G7]

Specifications

Product Data
Clone Name	G7
Applications	FC
Recommend Dilution	Flow cytometry: use 10 µl of neat antibody to label 10e6 cells in 100 µl.
Reactivity	Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Porcine peripheral blood leucocytes.
Specificity	This antibody recognises the porcine homologue of human CD16 (Fc gamma RIII alpha). CD16 is a low affinity FC gamma receptor expressed by polymorphonuclear cells (PMN), peripheral blood lymphocytes (PBL) and monocytes in pigs. Clone G7 has been reported to block PBL mediated antibody-dependent cell cytotoxicity (ADCC) and partially inhibit PMN-mediated ADCC.
Formulation	PBS with 0.09% sodium azide as preservative and 1% BSA as stabilizer. Label: FITC State: Liquid purified IgG Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Protein G chromatography
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for up to one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Database Link	UniProt ID Q28942
Background	CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in two forms CD16a and CD16b. CD16a is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. CD16b is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
Synonyms	FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.