Angiotensinogen (AGT) Mouse Monoclonal Antibody [Clone ID: BGN/0856/21 (08/56a/A2.21)]

Specifications

Product Data
Clone Name	BGN/0856/21 (08/56a/A2.21)
Applications	ELISA
Recommend Dilution	ELISA (1/10-1/100).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide representing Angiotensin II, conjugated to Rabbit Albumin.
Specificity	This antibody recognizes Angiotensin II and also Angiotensin I and III in ELISA. Incomplete mapping indicates the site of reactivity to be Val-Tyr-Ile-His-Pro[AI/II(3-8)], a conserved region of all angiotensin molecules.
Formulation	PBS buffer, pH 7.2 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	angiotensinogen
Database Link	Entrez Gene 183 Human UniProt ID P01019
Background	Angiotensin-I is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.
Synonyms	Angiotensin-2, Angiotensin-II, ANG2, ANG-2, ANG-II
Reference Data

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