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Species
Target Symbol
- P53 (110)
- BDNF (41)
- VEGFA (41)
- EGFR (37)
- CD44 (33)
- FGFR1 (28)
- KRAS (26)
- NRG1 (26)
- BIN1 (25)
- CD46 (25)
- PLAGL1 (25)
- DISC1 (24)
- MITF (24)
- CONSTITUTIVE ANDROSTANE RECEPTOR (23)
- HMGA1 (23)
- HNF 4 ALPHA (23)
- MAX (23)
- CAMK2D (22)
- PTGER3 (22)
- SPHK1 (22)
- CAMKK2 (21)
- FGFR2 (21)
- MET (21)
- TAU (21)
- CAMK2B (20)
- CAMK2G (20)
- KCNJ15 (20)
- MU OPIOID RECEPTOR (20)
- NDRG2 (20)
- OPA1 (20)
- PDE9A (20)
- RUNX2 (20)
- UBE2D3 (20)
- ALPHA 1 ANTITRYPSIN (19)
- BETA CATENIN (19)
- DYSTROBREVIN ALPHA (19)
- GABPB2 (19)
- MYADM (19)
- TFEB (19)
- TPM1 (19)
- TSPAN4 (19)
- APC11 (18)
- BHLHB9 (18)
- CD36 (18)
- CHRM2 (18)
- IGF1 (18)
- IGF2 (18)
- IRF5 (18)
- MEIS2 (18)
- MORTALITY FACTOR 4 LIKE 2 (18)
- RUNX1T1 (18)
- SNRPN (18)
- YAP1 (18)
- ALKALINE PHOSPHATASE (17)
- CEACAM1 (17)
- HGF (17)
- MBNL1 (17)
- MID1 (17)
- MYOSIN (17)
- NRAS (17)
- P2Y6 (17)
- RAD17 (17)
- RIBONUCLEASE INHIBITOR (17)
- SLC16A3 (17)
- SSH3BP1 (17)
- TGIF (17)
- 5HT4 RECEPTOR (16)
- ACRV1 (16)
- APOL3 (16)
- APRATAXIN (16)
- CCR6 (16)
- CPNE1 (16)
- CREM (16)
- EIF5A (16)
- FGF1 (16)
- GAPDH (16)
- IL32 (16)
- LAMP2 (16)
- MAGEA2 (16)
- NCALD (16)
- NUMB (16)
- OSBPL9 (16)
- P38 (16)
- PAX6 (16)
- PMP22 (16)
- PRKAR1B (16)
- RAB23 (16)
- RAB27A (16)
- RET (16)
- TCF7L2 (16)
- ALPHA DYSTROGLYCAN (15)
- AURORA A (15)
- CCR2 (15)
- CD82 (15)
- DNMT3B (15)
- ENPP2 (15)
- FGFR3 (15)
- GDNF (15)
- IL1RAP (15)
- KCNK2 (15)
Tags
Vectors
- pCMV6-Entry (56083)
- pCMV6-AC-GFP (16871)
- pCMV6-XL5 (9332)
- PCMV6-Kan/Neo (6078)
- pCMV6-XL4 (4366)
- pCMV6-AC (3731)
- pCMV6-XL6 (703)
- PCMV6-Neo (224)
- pCMV6-AC-Myc-DDK (144)
- pCMV6-XL5-DDK-His (73)
- pCMV6-Entry2 (17)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (12)
- pCMV6-AC-RFP (10)
- pCMV6-AC-mGFP (9)
- pCMV6-AC-mRFP (9)
- pCMV6-AC-mBFP (8)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (26226)
- Transmembrane (16223)
- Transcription Factors (6813)
- Secreted Protein (4447)
- Protein Kinase (2474)
- Protease (1650)
- ES Cell Differentiation/IPS (1613)
- Stem cell - Pluripotency (1363)
- GPCR (1265)
- Phosphatase (676)
- Ion Channels: Other (517)
- Adult stem cells (398)
- Nuclear Hormone Receptor (321)
- Embryonic stem cells (313)
- Ion Channels: Potassium (295)
- Cancer stem cells (218)
- P450 (176)
- Ion Channels: Cys-loop Receptors (172)
- Induced pluripotent stem cells (171)
- Stem cell relevant signaling - JAK/STAT signaling pathway (117)
- Ion Channels: Transient receptor potential (93)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (90)
- Stem cell relevant signaling - DSL/Notch pathway (83)
- Stem cell relevant signaling - Wnt Signaling pathway (76)
- Ion Channels: Glutamate Receptors (71)
- Ion Channels: Sodium (54)
- Ion Channels: Calcium (36)
- Ion Channels: ATP Receptors (32)
- Ion Channels: Cyclic nucleotide gated (25)
Pathways
- Metabolic pathways (3958)
- Pathways in cancer (1851)
- MAPK signaling pathway (1486)
- Cytokine-cytokine receptor interaction (1127)
- Neuroactive ligand-receptor interaction (1111)
- Regulation of actin cytoskeleton (974)
- Focal adhesion (926)
- Neurotrophin signaling pathway (875)
- Chemokine signaling pathway (839)
- Wnt signaling pathway (815)
- Endocytosis (811)
- Calcium signaling pathway (786)
- Huntington's disease (750)
- Prostate cancer (663)
- Insulin signaling pathway (648)
- Alzheimer's disease (641)
- Jak-STAT signaling pathway (641)
- Cell cycle (639)
- Natural killer cell mediated cytotoxicity (626)
- Purine metabolism (608)
- Axon guidance (605)
- Colorectal cancer (604)
- Olfactory transduction (585)
- Ubiquitin mediated proteolysis (585)
- Tight junction (576)
- ErbB signaling pathway (573)
- Melanoma (570)
- T cell receptor signaling pathway (563)
- Pancreatic cancer (559)
- Apoptosis (556)
- Progesterone-mediated oocyte maturation (551)
- Cell adhesion molecules (CAMs) (545)
- Melanogenesis (541)
- Oocyte meiosis (539)
- GnRH signaling pathway (536)
- Leukocyte transendothelial migration (529)
- Glioma (517)
- Chronic myeloid leukemia (516)
- Toll-like receptor signaling pathway (491)
- Small cell lung cancer (487)
- Vascular smooth muscle contraction (468)
- Endometrial cancer (464)
- Lysosome (457)
- Non-small cell lung cancer (453)
- Fc gamma R-mediated phagocytosis (452)
- Gap junction (449)
- p53 signaling pathway (449)
- Adherens junction (438)
- Hematopoietic cell lineage (438)
- Spliceosome (431)
- VEGF signaling pathway (431)
- Renal cell carcinoma (429)
- Parkinson's disease (419)
- Systemic lupus erythematosus (415)
- B cell receptor signaling pathway (403)
- Bladder cancer (403)
- Fc epsilon RI signaling pathway (396)
- Dilated cardiomyopathy (392)
- Oxidative phosphorylation (387)
- Long-term potentiation (386)
- Pyrimidine metabolism (377)
- Acute myeloid leukemia (376)
- Amyotrophic lateral sclerosis (ALS) (363)
- TGF-beta signaling pathway (359)
- Antigen processing and presentation (353)
- Hypertrophic cardiomyopathy (HCM) (353)
- Long-term depression (352)
- Basal cell carcinoma (337)
- Thyroid cancer (335)
- Adipocytokine signaling pathway (332)
- Epithelial cell signaling in Helicobacter pylori infection (332)
- NOD-like receptor signaling pathway (328)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (326)
- Complement and coagulation cascades (307)
- Ribosome (307)
- PPAR signaling pathway (305)
- Viral myocarditis (305)
- ECM-receptor interaction (298)
- RIG-I-like receptor signaling pathway (296)
- mTOR signaling pathway (290)
- Cardiac muscle contraction (268)
- Glycolysis / Gluconeogenesis (267)
- Phosphatidylinositol signaling system (263)
- Pathogenic Escherichia coli infection (253)
- Type II diabetes mellitus (245)
- Glycerophospholipid metabolism (243)
- Drug metabolism - cytochrome P450 (229)
- Vibrio cholerae infection (225)
- Cytosolic DNA-sensing pathway (224)
- Hedgehog signaling pathway (223)
- Metabolism of xenobiotics by cytochrome P450 (222)
- Arginine and proline metabolism (210)
- Valine (199)
- Inositol phosphate metabolism (198)
- Glutathione metabolism (197)
- Arachidonic acid metabolism (193)
- Autoimmune thyroid disease (191)
- RNA degradation (188)
- Retinol metabolism (188)
- Type I diabetes mellitus (184)
- Notch signaling pathway (175)
- Graft-versus-host disease (172)
- Taste transduction (172)
- Tyrosine metabolism (170)
- Fatty acid metabolism (169)
- N-Glycan biosynthesis (169)
- leucine and isoleucine degradation (169)
- Amino sugar and nucleotide sugar metabolism (166)
- Drug metabolism - other enzymes (166)
- Proteasome (166)
- Pyruvate metabolism (166)
- Glycerolipid metabolism (164)
- Primary immunodeficiency (162)
- Prion diseases (160)
- Nucleotide excision repair (158)
- Sphingolipid metabolism (157)
- Starch and sucrose metabolism (156)
- Lysine degradation (155)
- Allograft rejection (152)
- Cysteine and methionine metabolism (146)
- Alanine (143)
- aspartate and glutamate metabolism (143)
- ABC transporters (142)
- Tryptophan metabolism (142)
- Base excision repair (141)
- SNARE interactions in vesicular transport (140)
- Dorso-ventral axis formation (139)
- Fructose and mannose metabolism (136)
- Androgen and estrogen metabolism (129)
- Ether lipid metabolism (127)
- Maturity onset diabetes of the young (125)
- Citrate cycle (TCA cycle) (120)
- DNA replication (120)
- Propanoate metabolism (120)
- Porphyrin and chlorophyll metabolism (119)
- Aminoacyl-tRNA biosynthesis (117)
- Butanoate metabolism (114)
- Regulation of autophagy (113)
- Homologous recombination (110)
- Pentose phosphate pathway (110)
- Asthma (109)
- Galactose metabolism (109)
- Glycine (107)
- serine and threonine metabolism (107)
- Glycosphingolipid biosynthesis - lacto and neolacto series (104)
- Nicotinate and nicotinamide metabolism (102)
- Selenoamino acid metabolism (101)
- Basal transcription factors (100)
- Histidine metabolism (96)
- RNA polymerase (96)
- O-Glycan biosynthesis (94)
- Glycosaminoglycan degradation (90)
- Linoleic acid metabolism (88)
- Mismatch repair (88)
- Nitrogen metabolism (83)
- Phenylalanine metabolism (83)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (82)
- beta-Alanine metabolism (79)
- Heparan sulfate biosynthesis (78)
- Biosynthesis of unsaturated fatty acids (74)
- Renin-angiotensin system (73)
- Riboflavin metabolism (66)
- Chondroitin sulfate biosynthesis (65)
- Sulfur metabolism (64)
- Keratan sulfate biosynthesis (63)
- Pentose and glucuronate interconversions (63)
- Primary bile acid biosynthesis (63)
- Non-homologous end-joining (62)
- Other glycan degradation (62)
- Steroid biosynthesis (61)
- Ascorbate and aldarate metabolism (58)
- Glycosphingolipid biosynthesis - globo series (58)
- Pantothenate and CoA biosynthesis (58)
- Glyoxylate and dicarboxylate metabolism (56)
- One carbon pool by folate (56)
- Circadian rhythm - mammal (55)
- alpha-Linolenic acid metabolism (55)
- Terpenoid backbone biosynthesis (54)
- Glycosphingolipid biosynthesis - ganglio series (53)
- C21-Steroid hormone metabolism (45)
- Limonene and pinene degradation (45)
- leucine and isoleucine biosynthesis (42)
- Taurine and hypotaurine metabolism (41)
- Folate biosynthesis (37)
- Cyanoamino acid metabolism (32)
- Synthesis and degradation of ketone bodies (32)
- Fatty acid elongation in mitochondria (31)
- Caffeine metabolism (29)
- Protein export (29)
- Thiamine metabolism (29)
- Ubiquinone and other terpenoid-quinone biosynthesis (26)
- Fatty acid biosynthesis (25)
- Methane metabolism (21)
- Phenylalanine (21)
- tyrosine and tryptophan biosynthesis (21)
- Vitamin B6 metabolism (19)
- Lipoic acid metabolism (17)
- D-Glutamine and D-glutamate metabolism (13)
- Lysine biosynthesis (11)
- Biotin metabolism (9)
- O-Mannosyl glycan biosynthesis (9)
- D-Arginine and D-ornithine metabolism (3)