RNF183 (NM_145051) Human Recombinant Protein
CAT#: TP761858
Purified recombinant protein of Human ring finger protein 183 (RNF183), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
View other "RNF183" proteins (2)
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CNY 2,040.00
货期*
2周
规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length RNF183
|
Tag | N-GST and C-His |
Predicted MW | 49.4 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_659488 |
Locus ID | 138065 |
UniProt ID | Q96D59, A0A024R834 |
Refseq Size | 1237 |
Cytogenetics | 9q32 |
Refseq ORF | 576 |
Summary | Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PubMed:29507230). Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 (PubMed:29507230). May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849).[UniProtKB/Swiss-Prot Function] |
Protein Families | Druggable Genome, Transmembrane |
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