Calpain 1 (CAPN1) (NM_005186) Human Recombinant Protein
CAT#: TP761825
Purified recombinant protein of Human calpain 1, (mu/I) large subunit (CAPN1), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
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CNY 2,040.00
货期*
现货
规格
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length CAPN1
|
Tag | N-GST and C-His |
Predicted MW | 109.7 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_005177 |
Locus ID | 823 |
UniProt ID | P07384 |
Refseq Size | 3110 |
Cytogenetics | 11q13.1 |
Refseq ORF | 2142 |
Synonyms | CANP; CANP1; CANPL1; muCANP; muCL; SPG76 |
Summary | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Alzheimer's disease, Apoptosis |
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