SETD4 (NM_001007259) Human Recombinant Protein
CAT#: TP761421
Purified recombinant protein of Human SET domain containing 4 (SETD4), transcript variant 3, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
View other "SETD4" proteins (4)
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CNY 2,040.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length SETD4
|
Tag | N-GST and C-His |
Predicted MW | 62.9 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001007260 |
Locus ID | 54093 |
UniProt ID | Q9NVD3 |
Refseq Size | 1183 |
Cytogenetics | 21q22.12 |
Refseq ORF | 921 |
Synonyms | C21orf18; C21orf27 |
Summary | Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response (PubMed:31308046). Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively), leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity). Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3), thereby promoting heterochromatin formation (PubMed:31308046). Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) (By similarity).[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC413752 | SETD4 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC423476 | SETD4 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY413752 | Transient overexpression lysate of SET domain containing 4 (SETD4), transcript variant 1 |
CNY 4,840.00 |
|
LY423476 | Transient overexpression lysate of SET domain containing 4 (SETD4), transcript variant 3 |
CNY 3,080.00 |