TEC (NM_003215) Human Recombinant Protein
CAT#: TP760589
Purified recombinant protein of Human tec protein tyrosine kinase (TEC), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
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CNY 2,040.00
货期*
现货
规格
经常一起买 (2)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length TEC
|
Tag | N-His |
Predicted MW | 73.4 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_003206 |
Locus ID | 7006 |
UniProt ID | P42680 |
Refseq Size | 3620 |
Cytogenetics | 4p12-p11 |
Refseq ORF | 1893 |
Synonyms | PSCTK4 |
Summary | The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | T cell receptor signaling pathway |
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