Stanniocalcin 1 (STC1) Human Recombinant Protein
CNY 3,140.00
货期*
2周
规格
Product images
经常一起买 (1)
STC1 mouse monoclonal antibody,clone OTI6D12
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Thr18-Ala247
|
Tag | C-6His |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
Note | Recombinant Human Stanniocalcin 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 6781 |
UniProt ID | P52823 |
Synonyms | Stanniocalcin 1; stanniocalcin-1; STC1; STC-1; STCSTC-1 |
Summary | Stanniocalcin 1 (STC-1) is a homodimeric glycoprotein hormone that is involved in calcium and phosphate homeostasis. It was originally identified in bony fishes, where elevation of calcium in serum causes the release of STC from the endocrine glands called the corpuscles of Stannius. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. It is also a biomarker of brain and lung cancer progression. STC1 signals through inhibitory G-protein modulates CGRP receptor spatial localization during osteoblastogenesis and may function as a regulatory factor interacting with calcitonin peptide members during bone formation. |
Protein Families | Druggable Genome, Secreted Protein |
Documents
FAQs |
SDS |
其它Stanniocalcin 1产品
Customer
Reviews
Loading...