MECP2 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Ser486
Tag	C-His
Buffer	Lyophilized from a 0.2 um filtered solution of 20mMTris-HCl,300mMnacl,5% Trehalose,2mMDTT,ph8.0 .
Note	Recombinant Human Methyl-CpG-binding protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Ser486 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	4204
UniProt ID	P51608
Synonyms	Methyl-CpG-binding protein 2;MECP2;MeCp-2 protein
Summary	The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may also be necessary for the function of other types of brain cells.
Protein Families	Druggable Genome

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