BAX Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Gln171
Tag	N-6His, C-6His
Buffer	Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,2mM EDTA,5% Trehalose,30% Glycerol,pH7.4
Note	Recombinant Human BCL2-associated X protein is produced by our E.coli expression system and the target gene encoding Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Storage	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Locus ID	581
UniProt ID	Q07812
Synonyms	Bax; BCL2-associated X protein; Bcl2-L-4; BCL2L4
Summary	The Human Bax protein is a part of the anti-apoptotic BCL-2 family. This protein can transform from a cytosolic monomer into a dangerous mitochondrial oligomer. The Bax protein activates and transforms into a lethal oligomer that causes mitochondrial outer membrane permeabilization which commits human cells to apoptosis.
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, Neurotrophin signaling pathway, p53 signaling pathway, Pathways in cancer, Prion diseases

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.