Neuropilin 1 (NRP1) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Phe22-Lys644
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, 5% Trehalose, 0.01%Tween 80, pH7.4
Note	Recombinant Human Neuropilin-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Lys644 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	8829
UniProt ID	O14786
Synonyms	CD304; NRP1; NRPNP1; VEGF165R; BDCA4
Summary	Neuropilin-1, also known as vascular endothelial cell growth factor 165 receptor (VEGF165R), CD304, is a member of the neuropilin family. Neuropilin-1 is a receptor involved in multiple functions, including the development of the cardiovascular system, angiogenesis, the formation of certain neuronal circuits and organogenesis outside the nervous system. It also mediates the chemorepulsant activity of semaphorins. Neuropilin-1 can bind to semaphorin 3A, PLGF-2, VEGF-165, and VEGF-B. Coexpression of Neuropilin-1 with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis.
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	Axon guidance

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