Asialoglycoprotein Receptor 1 (ASGR1) Human Recombinant Protein

CAT#: TP724806

Recombinant Human Asialoglycoprotein Receptor Protein/ASGPR1 (C-His)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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经常一起买 (1)
Rabbit Polyclonal Anti-ASGR1 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag C-6His
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.2
Note Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 432
UniProt ID P07306
Synonyms Asialoglycoprotein Receptor 1; ASGP-R 1; ASGPR 1; C-Type Lectin Domain Family 4 Member H1; Hepatic Lectin H1; HL-1; ASGR1; CLEC4H1
Summary The asialoglycoprotein receptor (ASGPR) is an endocytotic cell surface receptor that is a member of the long-form subfamily of the C-type/Ca2+ dependent lectin family. ASGPR is expressed by hepatocytes and a subset of T cells and can be induced by triantennary binding to galactose residues of macromolecules. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR is reported to bind Gal (nonreducing), GalNAc, and sialic acid alpha 2,6Gal and GalNAc. Studies found that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development.
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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