Tnfsf13b (NM_033622) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	CHO
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Mouse BAFF, the region of Ala127-Leu309, from gene Accession# NM_033622
Tag	Tag Free
Predicted MW	22.8 kDa
Concentration	lot specific
Purity	>95%, as determined by Coomassie stained SDS-PAGE.
Buffer	1 x PBS, pH 6.5
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	The ED50 is 0.5 - 3 ng/ml, corresponding to a specific activity of 0.33 - 2.0 x 106 units/mg, determined by the dose dependent stimulation of B cells proliferation.
Endotoxin	Less than 1 EU per µg protein as determined by the LAL method
Reference Data
RefSeq	NP_296371
Locus ID	24099
UniProt ID	Q9WU72
Refseq Size	1710
Cytogenetics	8 4.55 cM
Refseq ORF	930
Synonyms	BAFF; BLyS; D8Ertd387e; TALL-1; TALL1; THANK; TNFSF20; Tnlg7a; zTNF4
Summary	Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.[UniProtKB/Swiss-Prot Function]

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