Il1a (NM_010554) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Mouse IL-1alpha;, the region of Ser115-Ser270, from gene Accession# NM_010554
Tag	Tag Free
Predicted MW	18 kDa
Concentration	lot specific
Purity	Purity is >98%, as determined by Coomassie stained SDS-PAGE.
Buffer	10 mM NaH2PO4, 150 mM NaCl, pH 7.2
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	The ED50 is 1- 5 pg/ml, corresponding to a specific activity of 1- 0.2 x 10^9 units/mg, determined by the dose dependent stimulation of D10S cells proliferation
Endotoxin	Less than 0.01 ng per ug protein as determined by the LAL method
Reference Data
RefSeq	NP_034684
Locus ID	16175
UniProt ID	P01582
Refseq Size	1974
Cytogenetics	2 62.9 cM
Refseq ORF	813
Synonyms	Il-1a
Summary	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.[UniProtKB/Swiss-Prot Function]

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