P4HB (NM_000918) Human Recombinant Protein
CAT#: TP720913XL
Purified recombinant protein of Human prolyl 4-hydroxylase, beta polypeptide (P4HB)
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CNY 26,600.00
货期*
2周
规格
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经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Asp18-Lys505
|
Tag | C-His |
Predicted MW | 55.9 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of PBS, pH 7.4. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_000909 |
Locus ID | 5034 |
UniProt ID | P07237, A0A024R8S5 |
Refseq Size | 2596 |
Cytogenetics | 17q25.3 |
Refseq ORF | 1524 |
Synonyms | CLCRP1; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB |
Summary | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
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