Nectin 3 (NECTIN3) (NM_015480) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Gly58-Cys366
Tag	C-His
Predicted MW	35 kDa
Concentration	lot specific
Purity	>95% as determined by SDS-PAGE and Coomassie blue staining
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM Tris,300mM NaCl,5% Trehalose,pH8.3.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin	< 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq	NP_056295
Locus ID	25945
UniProt ID	Q9NQS3
Cytogenetics	3q13.13
Synonyms	CD113; CDW113; NECTIN-3; PPR3; PRR3; PVRL3; PVRR3
Summary	This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Adherens junction, Cell adhesion molecules (CAMs)

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