TTI1 (NM_014657) Human Recombinant Protein
CAT#: TP710266
Purified recombinant protein of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), full length, with C-terminal DDK tag, expressed in sf9, 20ug
View other "TTI1" proteins (2)
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CNY 4,020.00
货期*
6周
规格
经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC201622, encoding human full-length TTI1
|
Tag | C-DDK |
Predicted MW | 121.9 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_055472 |
Locus ID | 9675 |
UniProt ID | O43156 |
Refseq Size | 3931 |
Cytogenetics | 20q11.23 |
Refseq ORF | 3267 |
Synonyms | KIAA0406; smg-10 |
Summary | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.[UniProtKB/Swiss-Prot Function] |
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