Akap7 (NM_018747) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR224507 representing NM_018747 Red=Cloning site Green=Tags(s) MPFAAVDIQDDCGSPDVPQANPKRSKEEEEDRGDKNDHVKKRKKAKKDYQPNYFLSIPITNKKITTGIKV LQNSILQQDKRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLALPFQGIGTF QGQVGFVKLADGDHVSALLEIAETAKRTFREKGILAGESRTFKPHLTFMKLSKAPMLRKKGVRKIEPGLY EQFIDHRFGEELLYQIDLCSMLKKKQSNGYYHCESSIVIGEKDRREPEDAELVRLSKRLVENAVLKAVQQ YLEETQNKKQPGEGNSTKAEEGDRNGDGSDNNRK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	35.9 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_061217
Locus ID	432442
UniProt ID	Q7TN79
Refseq Size	3140
Cytogenetics	10 A4
Refseq ORF	942
Synonyms	6430401D08; AI662165; AKAP15; Akap18; BB170514
Summary	Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity).[UniProtKB/Swiss-Prot Function]

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