Lzts2 (NM_001130526) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR224094 protein sequence Red=Cloning site Green=Tags(s) MAIVHTLPVPLEPARETATAPKTPAMGSVSSLISGRPCPGGPAPQRHHGVPGPTFFRQQDGLLRGGYEAQ EPLCPAVPPRKAVPGNSFTYVNEDFRTESPPSPSSDVEDPREHQAHNAHLRGPPPKLIPVSGKLEKNMEK ILIRPTAFKPVLPKPRGAPSLPGFLGPRAAGLSGSQGSLTQLFGGPASSSSSSSSSSAADKPLALSGWAS GCPSGTLSDSGRNSLSSLPTYSTGGAEPTTNSPGGHLPSHGPGRGALPGPARGVPTGPSHSDSGRSSSSK STGSLGGRVAGGLLGSGARASPGSSSGGDRSPPPPPPPPPSDEALLQCVLEGKLRDREAELQQLRDSMDE SEATVCQAFGARQRRWPRERGEDCAAQAQQATQRVQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQL ERRCATFEREQRELGPRLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVS EGRARGLQEAARAREQELEACSQELQRYRQEAERLREKAGHLDAEASGLRDPPVPPATTDPFLLAESDEA KVQRAAAGAGGSLRAQVERLRQELQREQRRGDEQRDSFEGERLAWQAEKEQVIRYQKQLQHNYIQMYRRN RQLEQELQQLSLELEARELADLGLAESAPCICLEEITATEI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	72.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001123998
Locus ID	226154
UniProt ID	Q91YU6
Refseq Size	2773
Cytogenetics	19 C3
Refseq ORF	2016
Synonyms	BC014695; LAPSER1; mKIAA1813
Summary	Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.[UniProtKB/Swiss-Prot Function]

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