Prex2 (NM_029525) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR218532 representing NM_029525 Red=Cloning site Green=Tags(s) MSDESAREVDKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAAAKVDKNVTEETVKMLFSNIE EILIVHKEFLKVVEECLYPEPSAQQEVGACFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLN CMLLGGRKNTDVPLEGYLVTPIQRICKYPLLLKELLKRTPRRHSDYTAVMEALQAMKAVCSNINEAKRQM EKLEVLEEWQAHIEGWEGSNITDTCTEMLMCGVLMKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKAS TDGYRYVFRGRINTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKSPEEKHEWFEAILK ERERRKGLKLGMEQDTWVMISEQGEKLYKMMCKQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRP EEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRSEMQDVISKGVRLYCRLHSLFTPVVR DKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFAVGLCDNGFMHHVLEKSEFKDEPLLFRFFADEE MEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFA INGDLVFLRPFPEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVA AAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYKRPMKQDSIQWVYDSLESAQEDIQKSHSKPPGD GAGDAFECKVEDVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGTKCNVVEKMVEPKGFFSL TAKILEALAKSDEHFVQNCTSLNSLNEVIATDLQSKFTSMCSERIEHVCHRISSYGRFSRVLKNRAWPTF KQAKPKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSVEPGKLSPMVYI QHTITTMAAPSGLSLGHKDGHGLQYLLKEEDLETQDIYHKLLGKLQTALKEVEMSVCQIDDLLSSITYSP KLERKTTECVTPMDSDNEKGERNSKRVCFNVAGDEQEDSGHDTVSNRDSYSDCNSNRNSIASFTSICSSQ CSSYFHSDEMDSGDELPISVRISHDKQDKIHTCLEQLFSQIDSIINLLKGQAVIRAFEQTKYLTPGRGLQ EFQQEMEAKLSCPRRLRLHLKQDPWNLPSSIQALAQSIRKHAEEVKCRILLALLEYSDSETQLRRDMVFC QSLVATVCAFSEQLMAALNQMFDNSKENEMETCEASRRWLDQIANAGVLFHFQSLLSPNLKDEQAMLEDT LVALFDLEKVSFFFKPSEEDPLVANVPLTYQVEGSRQALKVYFYMDSYHFEQLPQRLKNGGGFKIHPVLF SQALESMEGYCYRDNISVEEFQAQINTASLEKVKQYNQKLRAFYLDKSNSPPNTTSKAAYIDKLMKPLNA LDELYRLITSFIRSKRIAACVNTPCSASGVGLLSVSSELCDRLGACHIIMCSSGVHRCTLSVTLEQTITL ARSHGLPPRYIMQAMDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPVGEE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	181.7 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_083801
Locus ID	109294
UniProt ID	Q3LAC4
Refseq Size	11057
Cytogenetics	1 A2
Refseq ORF	4794
Synonyms	6230420N16Rik; AI316880; AI553603; C030045D06Rik; D430013K02; Depdc2; P-Rex2
Summary	Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase (By similarity).[UniProtKB/Swiss-Prot Function]

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