Mysm1 (NM_177239) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR216767 representing NM_177239 Red=Cloning site Green=Tags(s) MEAEEADVDVEGDVAAAAQPGNDESTASVFQDHYLDSTWRRENGCLPWTLDSTISDENRAIIEKMLLEEE YYLSNKSLPGKFWVNQKEDNKKYTNSLQKSSKAMVDSPAKPASHSVKWTVEEKELFEQGLAKFGRRWTKI ATLLKSRTVLQVKSYARQYFKNKVKWDVEKETPTQKSSSDLQVKNKDDRTKAWAAACLRGSADPCLNAVK IEKLSDDEDVDITDELDELTSQTSQNSGSHLTLDVPNSKMYTTNQGELCQEGPLAKSSGESLQNVKQGEG EACSSSEIASWAEKQKSTDKNSAELNEKYNKVVEEHTLHRGEVREEAKHSPSPEPCERQDSSGNEMLLPP CQIEEENHEGEELKPPEQEVEIDRNVIQEEEKQAIPEFFEGRQTKTPERYLKIRNYILDQWEICKPKYLN KTSVRPGLKNCGDVNCIGRIHTYLELIGAINFGCEQAVYNRPQPLDKVRAADRKDAEAAYQLAWRLQSMR TRRRRVRDPWGNWCDAKDLEGQTFEHLSVEEMARRKEEEKCKPIKFSKASKLPKSSLDPFQLIPCNFFSE EKQEPFQVKVAAEALLIMNLHAHVSMAEVIGLLGGRYSEADKVLEVCAAEPCNSLSTGLQCEMDPVSQTQ ASETLALRGYSVIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMIVSPYNRSNPLPYSQITCL VISEEVSPDGTYRLPYKFEVQQMLEEPQWELVFEKTRWIIEKYRLSNSSVPMDRIFRRDSDLTCLQKLLE CLRKTLSKVANCFIAEEFLTQIENLFLSNYKSKEENGLAEEDSTKELFM TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	93.9 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_796213
Locus ID	320713
UniProt ID	Q69Z66
Refseq Size	7420
Cytogenetics	4 C5
Refseq ORF	2457
Synonyms	C130067A03Rik; C530050H10Rik
Summary	Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation.[UniProtKB/Swiss-Prot Function]

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