Lrsam1 (NM_199302) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR210317 protein sequence Red=Cloning site Green=Tags(s) MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSL LPKSCSLLSLVTIKVLDLHENQLTALPDDMGQLTVLQVLNVERNQLTHLPRSIGNLLQLQTLNVKDNKLK ELPDTLGELRSLRTLDISENEIQRLPQMLAHVRTLETLSLNALAMVYPPPEVCGAGTAAVQQFLCKESGL DYYPPSQYLLPVLEQDGAENTQDSPDGPASRFSREEAEWQNRFSDYEKRKEQKMLEKLEFERRLDLGQRE HAELLQQSHSHKDEILQTVKQEQTRLEQDLSERQRCLDAERQQLQEQLKQTEQSIASRIQRLLQDNQRQK KSSEILKSLENERIRMEQLMSITQEETENLRQREIAAAMQQMLTESCKSRLIQMAYESQRQSLAQQACSS MAEMDKRFQQILSWQQMDQNKAISQILQESVMQKAAFEALQVKKDLMHRQIRNQIRLIETELLQLTQLEL KRKSLDTETLQEMVSEQRWALSNLLQQLLKEKKQREEELHGILAELEAKSETKQENYWLIQYQRLLNQKP LSLKLQEEGMERRLVALLVELSAEHYLPLFAHHRISLDMLSRMSPGDLAKVGVSEAGLQHEILRRAQDLL AVPRVQPELKPLENEVLGALEPPTAPRELQESVRPSAPPAELDMPTSECVVCLEREAQMVFLTCGHVCCC QQCCQPLRTCPLCRQEISQRLRIYHSS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	84 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_955006
Locus ID	227738
UniProt ID	Q80ZI6
Refseq Size	4002
Cytogenetics	2 B
Refseq ORF	2184
Synonyms	MGC56830
Summary	E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (viral proteins) cargos (By similarity). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (By similarity). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (By similarity).[UniProtKB/Swiss-Prot Function]

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