Cc2d1a (NM_145970) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR209260 representing NM_145970 Red=Cloning site Green=Tags(s) MHKRNGPQAPPGRGAVTARQLGLLVDFSPDGLMIPEDGINEEELEAEFLALVGGQPQALEKLKGQGPLPM EAIEKMARLCMRDLDEDEEGTDEDDVEADEDLLAELNEVLGEEQKAVEPLMPVAQPKPSGPNPGVEATLQ ERLTLYQSALESARQAGDSAKMRRYDRGLKTLENLLVSAKKGNIINEADIPPPVASGKGAAAGHSHTQAT SQLASVSPPAPESSGTLEAPSTTTPTSAKPQLPPDPCSPLARLQSLQHEYKLAALRAKHQDDTATATRHL RIAKSFDPVLEALSRGELVDLSRLPPPPDQLSPEPPLPAAQPLTSASTLTRPEVPQPPRNLLEALEQRME RYHVAAAQAKAKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPMQGLESAEPSQQSLVG VLETAMRLANHDEGSDDEEEETPKKQNTPAASTTQLKSSPSKAPPSGPAPAGKAAPKGTSNRAQQQLAFL EGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDIAKVPPAPVNKDDFVLVQRPGPG LSQEAVRRYGELTKLLRQQHEMCLNHSTQFTHLGNIAETIKFEKLAEDCKRSMDTLKQAFARSLPTPAAR FEQRTFSVIKVFPDLSNSDMLLFIVKGINLPTPTGLSPSDLDAFVRFDFPYPNVEEAQKDKTSVIKNTDS PEFKEQFKLCINRGHRGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLGTLETACEVHEILEVLDGR RPTGGRLEVMVRIREPLTAQQLETTTERWLVIDHIPAAMPTVTGPKAKAPLIPASSREAGNRSARPLHSL SVLAFDQERLERKILALRQARRPVPPEVAQQYQDVVQRSQWQRAQLEQGGAALRREYASHLERQLHFYTE AARRLGYDGSREAAKEALYRRNLVESELQRLRR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	103.7 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_666082
Locus ID	212139
UniProt ID	Q8K1A6
Refseq Size	3349
Cytogenetics	8 C2
Refseq ORF	2829
Synonyms	BC016188; Freud-1; Tape
Summary	Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses.[UniProtKB/Swiss-Prot Function]

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