Zgpat (NM_144894) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR208211 protein sequence Red=Cloning site Green=Tags(s) MDEDNLETALQTYRAQLQQVELALGAGLDASEQADLRQLQGDLKELIELTEASLLSVRKSKLLSTVDQES PAQEDAEYLAFQKAIAEEVEAPGAPCNDSETAPGSEVQPGSTSSALEEEEEDPDLEELSGAKVNAPYYSA WGTLEYHNAMVVGAEEAEDGSACVRVLYLYPTHKSLKPCPFFLEGKCRFKENCRFSHGQVVSVDELRPFQ DPDLSLLQTGSACLAKHQDGLWHPARITDVDNGYYTVKFDSLLLKEAVVEGDSILPPLRTEATESSDSDT GDASDSSYARVVEPSTVDTGTCSSAFAGWEVHTRGIGSKLLVKMGYEFGKGLGRHAEGRVEPIHAVVLPR GKSLDQCAEILQKKTKRGQAGSNRPPKCRRSGSRPEGRPPPRNVFDFLNEKLQSQVPGTPDAGVDTPERR NKDMYHASKSAKQALSLQLFQTEEKIERTQRDIRGIQEALTRNTGRHNMTTAHLQEKLEGAQRQLGQLRA QEADLQRKQRKADTHRKMTEF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	56.4 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_659143
Locus ID	229007
UniProt ID	Q8VDM1
Refseq Size	2289
Cytogenetics	2 H4
Refseq ORF	1536
Synonyms	1500006I01Rik; BC021513
Summary	Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity).[UniProtKB/Swiss-Prot Function]

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