Rnf135 (NM_028019) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR206607 protein sequence Red=Cloning site Green=Tags(s) MAAVCSGNAVPVWLSEDDLSCIICQGLLDQPTTLPCGHSFCLRCLHDLWVSKRGAVDGCPWACPICRKGP LTKPKLHKNPLLQDLVDKYLQAAREVEAGSEPEPAPAPRSAPQVTVQKSTTNVIQELTDMVRQLVDDVKS LQTQRPNLGSGQDNAQGTPPTDSSSEGEHSLDSPKLVTFSISQKKIQEILHNLEEIQEKLQGSVPGRAPP RERVQEMTSSLCLLPDQRRPAPRKASHLSLWAISPTFDLRTLSYNLEVSNNSRRVTVSRGDLHTYHWSPQ RFSISQVFCSQALSSGQKYWEVDTRNCSHWAIGVASWGMKRDGMLGRTMDSWCIEWRGPGQFSAWAKMKK TDLQSDLPEVVGVWLDLESGELAFYAVADHERLLYECEVSSSSPLHPAFWLYGLSPGNYLEIKQLNT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	46.5 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_082295
Locus ID	71956
UniProt ID	Q9CWS1, B2RRA5
Refseq Size	1959
Cytogenetics	11 47.59 cM
Refseq ORF	1254
Synonyms	0610037N03Rik; 2410006N06Rik
Summary	Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.[UniProtKB/Swiss-Prot Function]

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