Rita1 (NM_133908) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR203237 protein sequence Red=Cloning site Green=Tags(s) MKALHLQHRSPTSYRVKARASYVDETLFGSPARTRPAQPDFDPPWVQNCNRSRGVGPGPPKGSLAKRDCE SPSSRGSTPNLTPRKKNKYRLIGHAPSYCDESLFGTSKEGSRMAVGDAAKLRTLFWTPPATPRGSHTPCP RETPLRAIHPAGPSRTEPRVTAGSQMSSQDGLCVPCSLGQRRSHSLTHLTVPSTGHPASSAPQTNGPWSP RPNTSGATVQSPLVTSKACSGRVSGPAPPRRGACPPKPKPPWK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	27.1 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_598669
Locus ID	100764
UniProt ID	Q9D1H0
Refseq Size	1668
Cytogenetics	5 F
Refseq ORF	762
Synonyms	1110008J03Rik; AI853657; C86297; Rita
Summary	Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity).[UniProtKB/Swiss-Prot Function]

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