PABP (PABPC1) (NM_002568) Human Recombinant Protein
CAT#: TP307354
Recombinant protein of human poly(A) binding protein, cytoplasmic 1 (PABPC1), 20 µg
View other "PABP" proteins (3)
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Cited in 3 publications. |
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>Peptide sequence encoded by RC207354
Blue=ORF Red=Cloning site Green=Tag(s) MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSK GYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERL KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL KRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEE ATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIP QTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVA NTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLAS APPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKE AAQKAVNSATGVPTV SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC207354 also available, TP307354 |
Tag | C-Myc/DDK |
Predicted MW | 70.5 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002559 |
Locus ID | 26986 |
UniProt ID | P11940 |
Refseq Size | 2869 |
Cytogenetics | 8q22.3 |
Refseq ORF | 1908 |
Synonyms | PAB1; PABP; PABP1; PABPC2; PABPL1 |
Summary | This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010] |
Citations (3)
The use of this Proteins has been cited in the following citations: |
---|
CELF1 is an EIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs
,Chaudhury, A;Pal, R;Kongchan, N;Zhao, N;Zhu, Y;,
bioRxiv
[PABP]
|
PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay.
,null,
Molecular cell
,PubMed ID 29932901
[PABP]
|
Uridylation by TUT4 and TUT7 Marks mRNA for Degradation
,null,
Cell
,PubMed ID 25480299
[PABP]
|
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Other Versions
SKU | Description | Size | Price |
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LC419240 | PABPC1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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LY419240 | Transient overexpression lysate of poly(A) binding protein, cytoplasmic 1 (PABPC1) |
CNY 3,080.00 |
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PH307354 | PABPC1 MS Standard C13 and N15-labeled recombinant protein (NP_002559) |
CNY 19,520.00 |