Parathyroid hormone / PTH (32-115) Human Protein
CAT#: SA6052
Parathyroid hormone / PTH (32-115) human protein, 0.1 mg
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CNY 8,000.00
货期*
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规格
Cited in 2 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MSVSEIQLMH NLGKHLNSME RVEWLRKKLQ DVHNFVALGA PLAPRDAGSQ RPRKKEDNVL VESHEKSLGE ADKADVNVLT KAKSQ
|
Predicted MW | 9.55 kDa |
Concentration | lot specific |
Purity | >95% by SDS-PAGE |
Buffer | Presentation State: Purified State: Liquid protein Buffer System: Phosphate-Buffered Saline (PBS) containing 2 mM EDTA, pH 7.4 |
Preparation | Liquid protein |
Protein Description | Human Parathyroid Hormone (amino acids 32-115) was overexpressed in E. coli and purified to apparent homogeneity by using conventional column Chromatography techniques. |
Storage | Store at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_000306 |
Locus ID | 5741 |
UniProt ID | P01270 |
Cytogenetics | 11p15.3 |
Synonyms | FIH1; PTH1 |
Summary | This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
Protein Families | Druggable Genome, Secreted Protein |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
A tagged parathyroid hormone derivative as a carrier of antibody cargoes transported by the G protein coupled PTH1 receptor.
,null,
Peptides
,PubMed ID 25128082
[PTH]
|
C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cells
,null,
Frontiers in Pharmacology
,PubMed ID 24068998
[PTH]
|
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