Adiponectin (111-247) Mouse Protein
CAT#: SA6051
Adiponectin (111-247) mouse recombinant protein, 0.1 mg
Need it in bulk or customized? Get a free quote |
CNY 8,000.00
货期*
详询
规格
Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MAYMYRSAFS VGLETRVTVP NVPIRFTKIF YNQQNHYDGS TGKFYCNIPG LYYFSYHITV YMKDVKVSLF KKDKAVLFTY DQYQEKNVDQ ASGSVLLHLE VGDQVWLQVY GDGDHNGLYA DNVNDSTFTG FLLYHDTN
|
Predicted MW | 16 kDa |
Concentration | lot specific |
Purity | >95% by SDS-PAGE |
Buffer | Presentation State: Purified State: Liquid Buffer System: 20 mM Tris-HCl pH 7.5, 50 mM NaCl, 5 mM DTT, 10% Glycerol |
Preparation | Liquid |
Protein Description | Recombinant Adipocyte complement-related Protein (Mouse): The globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_033735 |
Locus ID | 11450 |
UniProt ID | Q60994 |
Cytogenetics | 16 13.96 cM |
Synonyms | 30kDa; Acdc; Acrp30; Ad; adipo; apM1; APN; GBP28 |
Summary | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.[UniProtKB/Swiss-Prot Function] |
Documents
FAQs |
SDS |
Customer
Reviews
Loading...