KITLG / SCF Human Protein
CAT#: DA3548S
KITLG / SCF human recombinant protein, 2 µg
Size: 10 ug
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CNY 3,260.00
货期*
7周
规格
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Predicted MW | 18.5 kDa |
Purity | >98% > 98% by RP-HPLC, Anion-exchange FPLC, Silver stain |
Buffer | Presentation State: Purified State: Lyophilized without stabilizer Buffer System: 10 mM acetic acid |
Preparation | Lyophilized without stabilizer |
Protein Description | Recombinant Human SCF |
Note | Centrifuge vials before opening! |
Storage | Prior and following reconstitution store (in aliquots) at 2 - 8 °C for up to two weeks or -20 °C for longer. For long term storage add a carrier protein (0.1 % HAS or BSA). Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Bioactivity | Biological: Recombinant human SCF is fully biologically active when compared to standards. The ED50 determined by the dose-dependent stimulation of human TF-1 cells is < 2.0 ng/ml. Specific: 1 x 10e5 units/mg |
Endotoxin | < 0.1 ng per µg (IEU/µg) of rh SCF |
Reference Data | |
RefSeq | NP_000890 |
Locus ID | 4254 |
UniProt ID | P21583, A0A024RBC0 |
Cytogenetics | 12q21.32 |
Synonyms | DCUA; DFNA69; FPH2; FPHH; Kitl; KL-1; MGF; SCF; SF; SHEP7; SLF |
Summary | This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer |
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