HCV NS3 (c33c (Genotype 1a, 1192-1459)) Protein

Specifications

Product Data
Expression Host	E. coli
Predicted MW	26 kDa
Concentration	lot specific
Purity	>95% pure by 10% PAGE. S-Sepharose, Ceramic Hydroxyapatite and Affinity Chromatography.
Buffer	Presentation State: Purified State: Liquid purified fraction Buffer System: 50 mM Sodium Phosphate, pH 8.3 containing 8 mM DTT without preservatives
Preparation	Liquid purified fraction
Applications	Suitable for use in ELISA and Western blot.
Protein Description	Recombinant Hepatitis C Virus (HCV) NS-3 c33c, (amino acids 1192-1459) Subtype 1a Contains full-length HCV c33c immunodominant region. Not full-length NS3. Contains 6 histidine fusion sequence. Immunoreactive with HCV positive sera including sera with antibodies to NS3 secondary structure domains.
Storage	Store the antigen (in aliquots) at -20°C. Avoid multiple freeze/thaw cycles.
Stability	Shelf life: six months from despatch.
Reference Data
Synonyms	Hepatitis C Virus Serine proteiase NS3
Summary	Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
Protein Families	Suitable for use in ELISA and Western blot.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.