STOML1 (79-398, His-tag) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MGSSHHHHHH SSGLVPRGSH MGSLKIVPTY ERMIVFRLGR IRTPQGPGMV LLLPFIDSFQ RVDLRTRAFN VPPCKLASKD GAVLSVGADV QFRIWDPVLS VMTVKDLNTA TRMTAQNAMT KALLKRPLRE IQMEKLKISD QLLLEINDVT RAWGLEVDRV ELAVEAVLQP PQDSPAGPNL DSTLQQLALH FLGGSMNSMA GGAPSPGPAD TVEMVSEVEP PAPQVGARSS PKQPLAEGLL TALQPFLSEA LVSQVGACYQ FNVVLPSGTQ SAYFLDLTTG RGRVGHGVPD GIPDVVVEMA EADLRALLCR ELRPLGAYMS GRLKVKGDLA MAMKLEAVLR ALK
Tag	His-tag
Predicted MW	37.0 kDa
Concentration	lot specific
Purity	>90% by SDS - PAGE
Buffer	Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl (pH 8.0) containing 10% glycerol
Preparation	Liquid purified protein
Protein Description	Recombinant human STOML1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_001243601
Locus ID	9399
UniProt ID	Q9UBI4, Q53HB6
Cytogenetics	15q24.1
Synonyms	hUNC-24; SLP-1; STORP
Summary	May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed:23082202).[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane

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