MIP3-beta / CCL19 (22-98, T7-tag) Human Protein
CAT#: AR09517PU-L
MIP3-beta / CCL19 (22-98, T7-tag) human recombinant protein, 0.5 mg
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CNY 13,720.00
货期*
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MASMTGGQQM GRGSHMGTND AEDCCLSVTQ KPIPGYIVRN FHYLLIKDGC RVPAVVFTTL RGRQLCAPPD QPWVERIIQR LQRTSAKMKR RSS
|
Tag | T7-tag |
Predicted MW | 10.4 kDa |
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified peptide Buffer System: PBS, pH 7.4, containing 10% glycerol |
Preparation | Liquid purified peptide |
Protein Description | Recombinant human CCL19 protein, fused to T7-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Endotoxin | < 1.0 EU per 1 μg of protein (determined by LAL method ) |
Reference Data | |
RefSeq | NP_006265 |
Locus ID | 6363 |
UniProt ID | Q99731, Q6IBD6 |
Cytogenetics | 9p13.3 |
Synonyms | CKb11; ELC; MIP-3b; MIP3B; SCYA19 |
Summary | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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