FGF12 (1-181, His-tag) Human Protein
CAT#: AR09110PU-L
FGF12 (1-181, His-tag) human recombinant protein, 0.5 mg
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CNY 23,950.00
货期*
详询
规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK ASLYVAMNGE GYLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ IMKGNRVKKT KPSSHFVPKP IEVCMYREQS LHEIGEKQGR SRKSSGTPTM NGGKVVNQDS T
|
Tag | His-tag |
Predicted MW | 22.6 kDa |
Concentration | lot specific |
Purity | >90% by SDS-PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris pH 7.5, 10% glycerol, 1 mM DTT, 2 mM EDTA |
Preparation | Liquid purified protein |
Protein Description | Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_004104 |
Locus ID | 2257 |
UniProt ID | P61328, P61328-2 |
Cytogenetics | 3q28-q29 |
Synonyms | DEE47; EIEE47; FGF12B; FHF1 |
Summary | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. [provided by RefSeq, Dec 2019] |
Protein Families | Secreted Protein |
Protein Pathways | MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton |
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