PSMD10 / Gankyrin (1-226) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG
Predicted MW	24.4 kDa
Concentration	lot specific
Purity	>95% > 95% by SDS PAGE
Buffer	Presentation State: Purified State: Liquid purified protein Buffer System: PBS (pH 7.4), 10% glycerol
Preparation	Liquid purified protein
Protein Description	Recombinant human Gankyrin was expressed in E.coli and purified by conventional chromatography techniques.
Note	NCBI Accession No.: NP_002805
Storage	Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_002805
Locus ID	5716
UniProt ID	O75832
Cytogenetics	Xq22.3
Synonyms	dJ889N15.2; p28; p28(GANK)
Summary	This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011]

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