AGR2 (21-175, His-tag) Human Protein
CAT#: AR09003PU-S
AGR2 (21-175, His-tag) human recombinant protein, 0.1 mg
Size: 500 ug
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CNY 8,900.00
货期*
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSRDTT VKPGAKKDTK DSRPKLPQTL SRGWGDQLIW TQTYEEALYK SKTSNKPLMI IHHLDECPHS QALKKVFAEN KEIQKLAEQF VLLNLVYETT DKHLSPDGQY VPRIMFVDPS LTVRADITGR YSNRLYAYEP ADTALLLDNM KKALKLLKTE L
|
Tag | His-tag |
Predicted MW | 21.9 kDa |
Concentration | lot specific |
Purity | >90% by SDS PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris 8.0, 10% glycerol, 1 mM EDTA |
Preparation | Liquid purified protein |
Protein Description | Recombinant human AGR2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_006399 |
Locus ID | 10551 |
UniProt ID | O95994, Q4JM46 |
Cytogenetics | 7p21.1 |
Synonyms | AG-2; AG2; GOB-4; HAG-2; HEL-S-116; HPC8; PDIA17; XAG-2 |
Summary | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] |
Protein Families | Secreted Protein |
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