Collagen type III alpha 1 chain Bovine Protein
CAT#: RA006
Collagen type III alpha 1 chain bovine protein, 0.5 mg
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CNY 6,000.00
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Specifications
Product Data | |
Description | Collagen type III alpha 1 chain bovine protein, 0.5 mg |
Species | Bovine |
Protein Source | Placenta |
Concentration | lot specific |
Purity | >98% Chromatographically and immunologically pure. |
Buffer | State: Liquid (sterile filtered) purified Ig fraction. Buffer System: 0.5M Acetic Acid, pH 4.5 containing 0.01% Sodium Azide as preservative and without stabilizers. |
Preparation | Liquid (sterile filtered) purified Ig fraction. |
Applications | Suitable for use as a control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for Immunoprecipitation and for Western blotting. |
Protein Description | This antigen has been prepared from bovine placenta and is free from other collagens, serum proteins and non-collagen extracellular matrix proteins. Reacts with anti-Collagen Type III. Reaction with anti-Collagen I, II, IV, V or VI is negligible (typically less than 1% cross reactivity was detected by ELISA. |
Storage | Store vial at 2-8°C prior to opening. This product is stable 2-8°C as an undiluted liquid. Dilute only prior to immediate use. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_000081 |
Locus ID | 1281 |
Cytogenetics | 2q32.2 |
Synonyms | EDS4A; EDSVASC; PMGEDSV |
Summary | This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
Protein Families | Druggable Genome |
Protein Pathways | ECM-receptor interaction, Focal adhesion |
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