Alpha-fetoprotein / AFP Human Protein
CAT#: BA1024
Alpha-fetoprotein / AFP human protein, 1 mg
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CNY 12,638.00
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规格
Cited in 1 publication. |
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Specifications
Product Data | |
Description | Alpha-fetoprotein / AFP human protein, 1 mg |
Species | Human |
Protein Source | Cell culture |
Concentration | lot specific |
Purity | >95% ≥95% pure by PAGE Electrophoresis and Western blot. |
Buffer | Presentation State: Aff - Purified State: Liquid (0.2 µm filtered) affinity purified fraction. Buffer System: 0.1M Tris, 0.2M Sodium Chloride, pH 7.5 Preservative: 0.09% Sodium Azide |
Preparation | Liquid (0.2 µm filtered) affinity purified fraction. |
Protein Description | Human Alpha Fetoprotein (AFP) Antigen Grade. |
Note | Caution: The cell line supernatant tested negative for HIV 1, HIV 2, and HCV antibodies, HIV Ag and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious. |
Storage | Short term (up to 14 days) store at 2-8°C. Long term, aliquot and store at -20°C. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001125 |
Locus ID | 174 |
Cytogenetics | 4q13.3 |
Synonyms | Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP |
Summary | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019] |
Protein Families | Druggable Genome, Secreted Protein |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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Noninvasive prediction of HCC with progenitor phenotype based on gadoxetic acid-enhanced MRI.
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European radiology
,PubMed ID 31529254
[AFP]
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