PTPRB (NM_001109754) Human Mass Spec Standard

CAT#: PH326479

PTPRB MS Standard C13 and N15-labeled recombinant protein (NP_001103224)



  View other "PTPRB" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of protein tyrosine phosphatase, receptor type, B (PTPRB), transcript variant 1
    • 100 ug

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PTPRB Rabbit pAb
    • 100 ul

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Specifications

Product Data
Description PTPRB MS Standard C13 and N15-labeled recombinant protein (NP_001103224)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226479
Predicted MW 249 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001103224
RefSeq ORF 6645
Synonyms HPTP-BETA; HPTPB; PTPB; R-PTP-BETA; VEPTP
Locus ID 5787
Cytogenetics 12q15
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Protein Families Druggable Genome, Phosphatase
Protein Pathways Adherens junction
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