LRRC8A (NM_001127244) Human Mass Spec Standard

CAT#: PH326180

LRRC8A MS Standard C13 and N15-labeled recombinant protein (NP_001120716)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description LRRC8A MS Standard C13 and N15-labeled recombinant protein (NP_001120716)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226180
Predicted MW 94.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001120716
RefSeq Size 4637
RefSeq ORF 2430
Synonyms AGM5; HsLRRC8A; LRRC8; SWELL1
Locus ID 56262
Cytogenetics 9q34.11
Summary This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Protein Families Transmembrane
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