VSX1 (NM_199425) Human Mass Spec Standard

Specifications

Product Data
Description	VSX1 MS Standard C13 and N15-labeled recombinant protein (NP_955457)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224272
Predicted MW	24.8 kDa
Protein Sequence	Sequence Link (showhide) >RC224272 representing NM_199425 Red=Cloning site Green=Tags(s) MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAVAPCPGPGLDG SSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPPPALGRQKRSDSVST SDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQV SGVPFLRSKDTTENVSFPHSVSQSAVPSL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_955457
RefSeq Size	943
RefSeq ORF	717
Synonyms	CAASDS; KTCN; KTCN1; PPCD; PPCD1; PPD; RINX
Locus ID	30813
Cytogenetics	20p11.21
Summary	The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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