FAK (PTK2) (NM_005607) Human Mass Spec Standard

CAT#: PH321398

PTK2 MS Standard C13 and N15-labeled recombinant protein (NP_005598)



  View other "FAK" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PTK2 MS Standard C13 and N15-labeled recombinant protein (NP_005598)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221398
Predicted MW 121.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005598
RefSeq Size 4442
RefSeq ORF 3222
Synonyms FADK; FADK 1; FAK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71
Locus ID 5747
Cytogenetics 8q24.3
Summary This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, Chemokine signaling pathway, ErbB signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer, VEGF signaling pathway
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